Table 2

Results of Btk mutational analysis


Patient 1
Patient 2

Nucleotide change
c.83G>A
c.1223T>C
Amino acid change
p.Arg28His
p.Leu408Pro
Domain
PH
SH1
Zygosity
Hemizygous
Hemizygous

PH, Pleckstrin Homology; SH1, Src homology 1

Sigmon et al. Clinical and Molecular Allergy 2008 6:5   doi:10.1186/1476-7961-6-5