Table 3 |
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|
HLA-DR and HLA-DQ allele frequencies in children with Alternaria-sensitive moderate-severe asthma compared to Alternaria-sensitive mild asthma. |
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|
Study |
Moderate-Severe (60) |
Mild (49) |
P |
|
|
|||
|
HLA-DRB1 |
|||
|
*01 |
10 (0.051) |
8 (0.041) |
|
|
*03 |
29 (0.153) |
20 (0.102) |
|
|
*04 |
14 (0.076) |
29 (0.153) |
|
|
*07 |
24 (0.127) |
27 (0.143) |
|
|
*08 |
7 (0.034) |
10 (0.061) |
|
|
*09 |
7 (0.034) |
4 (0.020) |
|
|
*10 |
2 (0.008) |
2 (0.010) |
|
|
*11 |
17 (0.093) |
33 (0.184) |
|
|
*12 |
7 (0.034) |
2 (0.010) |
|
|
*13 |
37 (0.195) |
20 (0.112) |
0.06 |
|
*14 |
3 (0.017) |
2 (0.010) |
|
|
*15 |
27 (0.161) |
27 (0.143) |
|
|
*16 |
3 (0.010) |
2 (0.010) |
|
|
HLA-DQB1 |
|||
|
*02 |
42 (0.254) |
33 (0184) |
|
|
*03 |
39 (0.220) |
63 (0.398) |
0.02 (0.007) |
|
*04 |
12 (0.068) |
8 (0.041) |
|
|
*05 |
31 (0.161) |
20 (0.102) |
|
|
*06 |
44 (0.288) |
51 (0.276) |
|
|
|
|||
|
Data presented as percentage of patients with allele and in parentheses allele frequency. P value using Fisher's exact test. |
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|
Knutsen et al. Clinical and Molecular Allergy 2010 8:5 doi:10.1186/1476-7961-8-5 |
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