Figure 2.

Alternaria-stimulated cytokine synthesis in Alternaria-sensitive moderate-severe asthma. IL-5 and IL-13 synthesis was significantly increased in Alternaria extract stimulated T cells by Alternaria-sensitive moderate-severe asthmatic patients compared to Alternaria-sensitive mild asthma (p = 0.008 and p = 0.004, respectively) and to Alt a1 stimulated T cells by Alternaria-sensitive moderate-severe asthmatic patients compared to Alternaria-sensitive mild asthma (p = 0.07 and p = 0.007, respectively). In Asp f3 and Der p stimulated cultures, there were no significant differences of IL-5 and IL-13 synthesis comparing Alternaria-sensitive moderate-severe asthmatic versus Alternaria-sensitive mild asthmatics. Data presented as Mean ± SD. P value using Mann-Whitney U test.