Table 1

Selected salient clinical data for each patient

Pt nr

Treatment

Side effects

maintenance dose

Ratio CD63 activation at 0,1/1

1

Traditional

fatigue

40000

1,07

2

traditional

weals

100000

1,05

3

traditional

weals

100000

0,82

4

traditional

weals, fatigue

100000

0,87

5

traditional, discontinued

heartbeat, nervousness

(20)

0,78

6

cluster, discontinued

itchy tongue

(1000)

0,78

7

cluster

hyperventilation

100000

0,65

8

cluster

none

100000

0,95

9

cluster

none

100000

0,66

10

cluster

weals, itch, fatigue

100000

0,91

11

cluster

weals

100000

0,87

12

cluster

none

100000

0,71

13

cluster

weals

60000

0,51

14

cluster

weals

100000

1,22

15

cluster

weals, fatigue

100000

1,00

16

change

weals, oedema

100000

0,66

17

change

weals, fatigue

100000

0,59

18

change

weals

100000

2,09

19

change

weals

100000

1,36

20

change

weals

100000

1,13

Side effects, maintenance dose and CD63 activation at 0,1 ug/ml venom/1 ug/ml venom are listed against SCIT regimen (traditional 16 week up-dosing protocol/7 week cluster up dosing protocol/change from 7 week to 16 week protocol) applied. Where the ratio of activation exceeds 0,95 it has been shown to be predictive of side effects [7] and is printed bold. Side effects were weals around the site of injection

Mikkelsen et al. Clinical and Molecular Allergy 2010 8:2   doi:10.1186/1476-7961-8-2