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Value of eight-amino-acid matches in predicting the allergenicity status of proteins: an empirical bioinformatic investigation

Rod A Herman email, Ping Song email and Arvind ThirumalaiswamySekhar email

Dow AgroSciences LLC, 9330 Zionsville Road, Indianapolis, IN 46268, USA

author email corresponding author email

Clinical and Molecular Allergy 2009, 7:9doi:10.1186/1476-7961-7-9

Published: 29 October 2009

Additional files

Additional file 1:

8-mer-only pairs where both proteins are ≥80 amino acids. Each row contains information for pairs of sequences that are both ≥80 amino acids in length and that share an identical 8-amino-acid stretch, but do not share >35% homology over 80 amino acids. Initial rows in the table show sequence pairs with low-complexity matches falling outside of the FASTA alignment, followed by low-complexity matches within the FASTA alignment. Next are two sequence matches that only share a 9-amino-acid FASTA sequence alignment. Finally, ten complex matches within the FASTA alignment are shown.

Format: PPT Size: 72KB Download file

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Additional file 2:

Statistics based on minimum sequence length in 8-mer-only pairs. Number of FARRP entries, 8-mer-only pairs, and 8-mer-only pairs per protein for four different amino-acid-length classes grouped by the smaller protein in each pair.

Format: PPT Size: 53KB Download file

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Additional file 3:

8-mer-only pairs where the shorter protein contains 39 to 79 amino acids. Each row contains information for pairs of sequences where the shorter sequence is from 39 to 79 amino acids in length and that share an identical 8-amino-acid stretch, but do not share >35% homology over 80 amino acids.

Format: PPT Size: 64KB Download file

This file can be viewed with: Microsoft PowerPoint Viewer


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