|
Genotype distribution and p-values for association |
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| Polymorphism |
Genotype distribution |
p-values for association |
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|
|
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| Asthma |
RSV |
Controls |
Asthma- Controls |
RSV- Controls |
Asthma- RSV |
|
| IL8 rs4073 (-251A/T) |
64; 148; 101 |
26; 73; 34 |
70; 124; 74 |
0.087 |
0.550 |
0.425 |
| IL8 rs2227306 (-781C/T) |
123; 147; 48 |
37; 62; 27 |
84; 124; 61 |
0.011 |
0.937 |
0.034 |
| IL8RA rs16858811 (M31R) |
299; 20; 0 |
128; 7; 0 |
245; 25; 0 |
0.174 |
0.152 |
0.655 |
| IL8RA rs16858809 (S276T) |
239; 30; 0 |
121; 14; 0 |
121; 14;0 |
0.409 |
0.812 |
0.376 |
| IL8RA rs16858808 (R335C) |
298; 21; 0 |
127; 7; 0 |
246; 23; 1 |
0.239 |
0.171 |
0.584 |
|
The genotype distribution within the three different populations is given in the following order: homozygous wildtype, heterozygous and homozygous mutation. Also listed are the p-values for association with the diseases as calculated by the Armitage's trend test. | ||||||
Puthothu et al. Clinical and Molecular Allergy 2006 4:2 doi:10.1186/1476-7961-4-2 |
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