Table 4

Correlation between Maternal Stool Bacteria and Cord Blood Cytokine Secretion by Mode of Delivery



Vaginal Delivery (n = 22)
Cesarean Delivery (n = 15)




Maternal Stool Bacteria
Stimulant
Cytokines



IL-13



Gram-negative aerobes (Enterobacteriae)







rs*
p-value
rs*
p-value


Media
-0.38
0.08
0.52
0.06

Fel d 1
-0.25
0.27
0.39
0.17

Der f 1
-0.46
0.03
0.25
0.38

PHA
-0.28
0.21
-0.30
0.30

LPS
-0.35
0.11
0.14
0.62

Gram-negative anaerobes (Bacteroides/Prevotella)







rs*
p-value
rs*
p-value


Media
-0.27
0.22
0.59
0.03

Fel d 1
-0.22
0.34
0.70
0.006

Der f 1
-0.40
0.07
0.49
0.07

PHA
-0.29
0.18
-0.36
0.21

LPS
-0.07
0.77
0.57
0.03



IFN-γ



Gram-negative aerobes (Enterobacteriae)







rs*
p-value
rs*
p-value


Media
-0.52
0.01
-0.10
0.73

Fel d 1
-0.53
0.01
0.04
0.90

Der f 1
-0.47
0.03
0.04
0.90

PHA
-0.35
0.11
0.14
0.64

LPS
-0.50
0.02
0.22
0.44

Gram-negative anaerobes (Bacteroides/Prevotella)







rs*
p-value
rs*
p-value


Media
-0.34
0.13
0.24
0.40

Fel d 1
-0.30
0.17
0.36
0.21

Der f 1
-0.41
0.06
0.45
0.11

PHA
-0.19
0.40
0.49
0.07

LPS
-0.15
0.50
0.58
0.03



IL-10



Gram-positive anaerobes (lactobacilli/bifidobacteria)







rs*
p-value
rs*
p-value


Media
0.35
0.11
±
---

Fel d 1
0.43
0.04
0.15
0.62

Der f 1
0.45
0.03
0.30
0.30

PHA
-0.02
0.94
0.23
0.44

LPS
-0.03
0.89
0.23
0.42

Total Anaerobes







rs*
p-value
rs*
p-value


Media
0.26
0.25
±
----

Fel d 1
0.48
0.03
0.12
0.69

Der f 1
0.42
0.05
0.08
0.78

PHA
0.25
0.26
-0.22
0.44

LPS
0.26
0.25
-0.22
0.45

*Spearman's correlations.

± Correlation coefficients were not statistically obtainable due to undectectable IL-10 levels in the media samples (unstimulated CBMCs) among subjects in the cesarean section group.

Ly et al. Clinical and Molecular Allergy 2006 4:13   doi:10.1186/1476-7961-4-13