|
Association between Cytokine Secretion by CBMCs and Mode of Delivery |
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| Cytokine Levels (pg/ml) |
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|
|
||||||||
| Vaginal Delivery (n = 22) |
Cesarean Section (n = 15) |
|||||||
| median |
ranges |
% with Detectable Value± |
median |
ranges |
% with Detectable Value± |
wilcoxon p-value† |
||
|
|
||||||||
| IL-13 |
||||||||
| Media |
0.01* |
0.01–47.58 |
40.9 |
3.77 |
0.01–32.96 |
57.1 |
0.25 |
|
| Fel d 1 |
0.01 |
0.01–66.27 |
33.3 |
10.40 |
0.01–126.38 |
71.4 |
0.04 |
|
| Der f 1 |
0.01 |
0.01–75.65 |
40.9 |
26.14 |
0.01–65.61 |
85.7 |
0.01 |
|
| PHA |
25.18 |
0.01–223.54 |
63.6 |
39.31 |
7.50–246.04 |
100.0 |
0.22 |
|
| LPS |
5.46 |
0.01–565.55 |
50.0 |
20.19 |
0.01–44.65 |
78.6 |
0.39 |
|
| IFN-γ |
||||||||
| Media |
3.69 |
0.01–53.02 |
50.0 |
6.32 |
0.01–39.75 |
85.7 |
0.24 |
|
| Fel d 1 |
1.24 |
0.01–52.00 |
50.0 |
9.22 |
0.01–34.18 |
85.7 |
0.41 |
|
| Der f 1 |
8.10 |
0.01–58.93 |
59.1 |
16.52 |
0.01–54.95 |
85.7 |
0.43 |
|
| PHA |
11.10 |
0.01–173.58 |
63.6 |
23.23 |
0.01–866.65 |
85.7 |
0.38 |
|
| LPS |
20.03 |
0.01–218.70 |
68.2 |
15.21 |
0.01–85.27 |
85.7 |
0.97 |
|
| IL-10 |
||||||||
| Media |
0.01 |
0.01–49.96 |
18.2 |
0.01 |
0.01–0.01 |
0 |
0.10 |
|
| Fel d 1 |
0.01 |
0.01–355.80 |
27.3 |
0.01 |
0.01–78.57 |
14.3 |
0.37 |
|
| Der f 1 |
0.01 |
0.01–399.46 |
36.4 |
0.01 |
0.01–175.30 |
28.6 |
0.44 |
|
| PHA |
21.50 |
0.01–759.45 |
59.1 |
0.01 |
0.01–367.98 |
42.9 |
0.23 |
|
| LPS |
181.91 |
0.01–787.56 |
95.5 |
259.11 |
0.01–863.05 |
78.6 |
0.65 |
|
|
*Low value of 0.01 was assigned to undetectable cytokine level. ± Percentage of cord blood samples in which cytokine measured by ELISA have detectable values within each category of mode of delivery. † For comparison of cord blood cytokines between neonates born by vaginal delivery and those born by cesarean section. | ||||||||
Ly et al. Clinical and Molecular Allergy 2006 4:13 doi:10.1186/1476-7961-4-13 |
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