Table 8

Fracture Risk Reduction in Response to Therapy.

Generic Name
Brand Name
Spine Fracture
Non-Vertebral Fracture
Hip Fracture

Estrogen
Various



Alendronate
Fosamax



Risedronate
Actonel



Ibandronate
Boniva



Calcitonin
Miacalcin



Raloxifene
Evista



Teriparatide
Forteo




This table illustrates the direction of change in fracture risk with each type of drug. This does not represent a comparison of the magnitude of fracture risk reduction with different drugs. While all FDA-approved medications have been shown to reduce the risk of spine fracture, only estrogen, alendronate, and risedronate have reduced the risk of hip fracture in randomized placebo-controlled trials.

Lewiecki Clinical and Molecular Allergy 2004 2:9   doi:10.1186/1476-7961-2-9