|
Treatment strategies for eosinophilic gastritis |
||
| Strategy |
Intervention |
Comments |
|
|
||
| Diet |
elimination, food avoidance, elemental amino acid diet, total parenteral alimentation |
allergic patient allergic patient poor tolerance and cost only in severe patient |
| Antihelminthics |
mebendazole, others |
emperic trial, endemic areas |
| Mast cell stabilizer |
cromoglycate sodium |
allergic patient, anecdotal cases, administer QID, therapeutic trial |
| Glucocorticoids |
prednisone or equivalent |
lowest dose, taper, alternate day therapy, many adverse effects |
| Montelukast |
tablet given once/day |
leukotriene blocker, only anecdotal evidence |
| Ketotifen |
available in Canada |
investigational |
| Azathioprine |
immunosupressive |
bone marrow suppression |
| Others |
cyclophosphamide, hydroxyurea, cyclosporine A |
investigational investigational investigational |
| Biologicals |
antibody to IL-5, antibody to CCR3, antibody to IgE |
investigational investigational investigational (Food allergy) |
| Antibiotics |
ciprofloxacin, metronidazole |
for malabsorption bacterial overgrowth |
Copeland et al. Clinical and Molecular Allergy 2004 2:7 doi:10.1186/1476-7961-2-7 |
||