Both knockout mice show increased inflammation and mucus secretion post OVA compared to WT. Paraffin sections of lungs of OVA-treated mice were stained with A, Hematoxyline and eosin (10×), B. with Masson's Trichrome stain (20×), and C. Alcian blue counterstained with eosin (10×). Sections were viewed with a BX4l Olympus microscope and photomicrographs taken with a Nikon Spot digital camera. Inflammatory cell migration was more pronounced around airways in the OVA-treated knockout mice compared to control.
Banerjee and Henderson Clinical and Molecular Allergy 2012 10:2 doi:10.1186/1476-7961-10-2